Hormones

Hypothalamus

GnRH




Anterior pituitary

FSH

Unlocks at 4e+4 GnRH units

LH

Unlocks at 4e+4 GnRH units




Granulosa cells

Estrogen

Produced by granulosa cells

Inhibin

Produced by granulosa cells

Progesterone

Produced by granulosa cells
Unlocks at 1.00e+10 LH units

Thecal cells

Androgens
(To be converted to estrogen)

Produced by thecal cells

Upgrades

Double the speed of GnRH production

Cost: 400 GnRH units

Triple the speed of GnRH production

Cost: 1.00e+5 GnRH units

Antral follicle formation
Thecal cells respond to LH, granulosa cells respond to FSH

Cost: 2.00e+6 LH units and 2.00e+6 FSH units

Unlock slider to control activation ratio of granulosa and thecal cells

Cost: 3.00e+6 estrogen units

Buying upgrades no longer spends resources


Cost: 1.00e+6 estrogen units

Thecal layer becomes hyperaemic
Quadruple the speed of androgen production

Cost: 5.00e+6 LH units

Estrogen uses a better formula to stimulate its own production

Cost: 1.00e+7 estrogen units

Estrogen exerts positive feedback effects on GnRH, LH and FSH instead

Cost: 2.00e+8 estrogen units

Induce ovulation
Progesterone is produced much faster

Cost: 1.00e+13 LH units (LH surge required)

Corpus luteum matures
Boost progesterone, androgen and estrogen production

Cost: 3.00e+6 progesterone units

Undergo menstruation
Complete menstrual cycle
This will reset your progress, but you will gain 1 cycle point

Requirement: <1000 progesterone units

70% thecal cells, 30% granulosa cells


Cycles

Cycles completed:

0

Cycle points left:

0

Triple the speed of GnRH production

Cost: 1 cycle point

Autobuy upgrades (excludes cycle upgrades)

Cost: 2 cycle points

Estrogen exerts less negative feedback on GnRH, LH and FSH

Cost: 1 cycle point

Progesterone falls much faster after luteolysis

Cost: 1 cycle point

"Corpus luteum matures" upgrade cost is divided by 5

Cost: 1 cycle point

How the graph would look ideally...

Image taken from Encyclopedia Britannica

Welcome to the incremenstrual game!
Your goal is to buy all the upgrades to complete the menstrual cycle.

Read any blue messages you missed here: